How long do osteochondral allografts last?

Overall, osteochondral allografts to treat chondral lesions of the tibial plateau provide significant functional improvement for 10 years; however, less than 50 % are expected to survive 20 years [35•, 36].

How much does an osteochondral allograft cost?

Osteochondral allograft transplantation The downsides of this technique are graft availability, cost (with grafts approaching upward of $10,000), and the risk of disease transmission.

What is osteochondral repair?

In fact, the osteochondral repair process relies on progenitor cells or stem cells from the bone marrow to regenerate cartilage and bone tissue by allowing cell recruitment into the defect region.

What is osteochondral connect?

The osteochondral unit is composed of hyaline cartilage connected through a zone of calcified cartilage to the subchondral cortical bone known as the subchondral plate, which gives way to metaphyseal trabecular bone.

What is osteochondral allograft surgery?

An osteochondral allograft is a piece of tissue containing bone and cartilage that is taken from a deceased donor to replace damaged cartilage that lines the ends of bones in a joint.

What is a fresh osteochondral allograft?

Fresh osteochondral allograft (OCA) transplantation involves the transfer of size-matched allograft cartilage and subchondral bone into chondral or osteochondral defects of the knee.

What is osteochondral autograft?

Osteochondral autograft transfer (OATS) involves harvesting bone and intact articular cartilage from a less weight bearing portion of the knee to fill the defect in the weight bearing portion. It can be performed arthroscopically.

What is osteochondral allograft transplantation?

Osteochondral grafting is a method of treating cartilage injuries that expose underlying bone. An osteochondral allograft is a piece of tissue containing bone and cartilage that is taken from a deceased donor to replace damaged cartilage that lines the ends of bones in a joint.

What is a osteochondral defect?

An osteochondral defect refers to a focal area of damage that involves both the cartilage and a piece of underlying bone. These can occur from an acute traumatic injury to the knee or an underlying disorder of the bone.

What is osteochondral grafting?

What is osteochondral structure?

Osteochondral tissue is predominately composed of articular cartilage (hyaline cartilage) and a subchondral bone region. The depth-dependent composition, organisation, and structure are responsible for the biomechanical properties of the tissue (Klein et al., 2007).

What causes osteochondral?

Osteochondral lesions are usually caused by an injury, such as an ankle sprain, which damages the cartilage and forces it to soften and slowly break off. A broken piece of cartilage may remain in the ankle, causing an osteochondral lesion to occur.